Centro Europeo de Excelencia de Investigación en Vacuna
 

Area description
 
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Description
 

 

Research group
 
 
Head of Area
Javier Díez-Domingo
 

Senior Researcher
Joan Puig-Barberà
Àngels Natividad Sancho

Researchers
Silvia Pérez Vilar
Macrina Sastre Cantón
Mª Carmen Llopis García
Cintia Muñoz Quiles
 

Clinical Trials
Begoña Escribano-López
Esther Soriano García
Eva Jara Castillejo
Marian Martín Navarro
 
Statisticals
Ainara Mira Iglesias
Mónica López Lacort
 

 

 


Research group history
 

 

Vaccine Research
 
 

 

Objectives

The Vaccine Research Department studies the impact that infectious disease, which can be prevented by vaccination, has on society. This involves an understanding of the social burden and costs associated with disease. The vaccines are studied for effectiveness during routine vaccination programmes in the Valencian region, with the use of epidemiological studies of the disease before and after the start of vaccination.

The department carries out the clinical development of vaccines, studies on the vaccine safety and effectiveness, and designs and implements studies (clinical trials) allowing for changes to be made in vaccination guidelines, ensuring coordination with the vaccination calendar.
           

     

 

Lines of Research

1. Observational Studies

Development of networks of strategically placed researchers at primary or hospital care level.

Valencia Hospital Network for the Study of Influenza and Other Respiratory Viruses

2. Clinical Trials

Clinical trials of interest in public health are performed in collaboration with industry, providing training for health technicians, enabling them to carry out the studies. In-house clinical trials are monitored using external CRO.

3. Models, Economics, Evaluation and Vaccine Safety

Development of mathematical models for infectious diseases, used to estimate the impact that the diseases may have on various vaccines and vaccination calendars. Vaccine effectiveness is analysed and recommendations are made for vaccination guidelines. Pharmaeconomic analysis. Analysis of vaccine safety and the serious and rare side effects, conducted in collaboration with other areas of the CSISP, using health databases. Studies of the effectiveness of various strategies which could be used in the event of flu pandemics, bioterrorism attacks, etc, posing a threat to the population.

     

 

InternacionalProjects

ENSURE

Enabling kNowledge Sustainability Usability and Recovery for Economic value

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ADVANCE

Vaccine benefit-risk collaboration in Europe

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CAP-PRI

Community Adquired Pneumonia - Pediatric Research Initiative